Coordinated Youth & Human Services (CYHS) is a non-for-profit social service agency serving Granite City, Madison and Venice, and surrounding communities in southwestern Illinois.  CYHS was founded in 1944 in direct response to the need for delinquency services in Granite City.  The agency’s original name was Coordinated Youth Services. The agency's original name was changed to include Human Services diverse programs were added and extended beyond youth programs. As the needs of the community has changed over the years, so have the programs and services provided by CYHS.

Education of at-risk students has been a cornerstone of CYHS since its inception. In cooperation with the Granite City School District, Truancy has been working to improve school attendance for over 40 years. The Alternative Educational Program (AEP) started in 1973 to serve students who have demonstrated lack of success in traditional school programs. Next the Educational  Enhancement Program (EEP) was established in 1991. This program offers individualized educational plans for students and their families.

The Women, Infants and Children program (WIC) has been serving all of Madison County since 1974, with nutrition education and breastfeeding support. The Family Case Management (FCM) was added to CYHS in 2000 and is a companion program to WIC to better serve these families. The following year, in 2001, Healthy Families Illinois (HFI) started, with an emphasis on first time parents.

The Madison County AIDS program (MadCAP) was established in 1986 to prevent the spread of HIV and respond to the needs of people and their families affected by HIV. Case management services assist HIV positive clients, while counseling, testing and educational services have been added to reduce the risk and spread of the disease.

The Prevention Program has been providing education and support services to parents, teachers, youth and other community members since 1990. This includes the Teen REACH after school program, Tri-Cities Drug Free Communities, CHOICES life skill sessions and RAINBOW grief and loss support groups.

As CYHS has responded to the community needs, the facilities to support these services has changed over the years. In November 1993, the agency moved to its current building on Madison Avenue, where all the Granite City programs were under one roof. However, as the programs grew and expanded, the need for additional space arose. The Educational programs were able to lease space from the Granite City School District at Lake School starting in 2000. The Educational programs moved in October 2007 to the River's Edge with the opening of a new 19,500 square feet building specifically designed to serve the student population CYHS serves.